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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS39
All Species:
37.88
Human Site:
S278
Identified Species:
69.44
UniProt:
Q96JC1
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96JC1
NP_056104.2
886
101809
S278
E
P
R
L
L
V
Q
S
I
E
L
Q
R
P
R
Chimpanzee
Pan troglodytes
XP_510331
886
101752
S278
E
P
R
L
L
V
Q
S
I
E
L
Q
R
P
R
Rhesus Macaque
Macaca mulatta
XP_001102792
886
101693
S278
E
P
R
L
L
V
Q
S
I
E
L
Q
R
P
R
Dog
Lupus familis
XP_849407
886
101720
S278
E
P
R
L
L
V
Q
S
I
E
L
Q
R
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5L3
886
101674
S278
E
P
R
L
L
V
Q
S
I
E
L
Q
R
P
R
Rat
Rattus norvegicus
XP_001075756
886
101629
S278
E
P
R
L
L
V
Q
S
I
E
L
Q
R
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518189
1309
145152
I701
H
P
R
S
T
Q
E
I
P
L
M
D
R
D
R
Chicken
Gallus gallus
NP_001026365
875
100503
S267
E
P
R
L
L
V
Q
S
I
E
L
Q
R
P
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A4IG72
863
97029
T281
L
D
Q
Q
L
K
Q
T
L
S
F
R
D
G
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650702
876
100146
W266
S
P
L
L
D
L
V
W
D
E
P
F
A
V
G
Honey Bee
Apis mellifera
XP_392710
866
100055
T272
E
G
C
L
H
I
Q
T
I
K
D
L
N
K
A
Nematode Worm
Caenorhab. elegans
NP_001041163
923
104932
T290
F
D
G
Q
L
V
Q
T
M
S
L
P
K
A
M
Sea Urchin
Strong. purpuratus
XP_798217
824
94304
S272
D
P
R
L
L
V
Q
S
I
E
V
D
K
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.3
98
N.A.
97.4
96.8
N.A.
59.2
92.7
N.A.
26.4
N.A.
35.4
42.4
31.7
51.5
Protein Similarity:
100
99.8
99.7
99.3
N.A.
98.9
98.5
N.A.
62.8
96.1
N.A.
46.8
N.A.
55.6
62
52.5
68.4
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
26.6
100
N.A.
13.3
N.A.
20
26.6
26.6
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
40
100
N.A.
46.6
N.A.
26.6
46.6
46.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
16
0
0
8
0
0
0
8
0
8
16
8
8
0
% D
% Glu:
62
0
0
0
0
0
8
0
0
70
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% F
% Gly:
0
8
8
0
0
0
0
0
0
0
0
0
0
8
8
% G
% His:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
8
70
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
8
0
0
16
8
8
% K
% Leu:
8
0
8
77
77
8
0
0
8
8
62
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
77
0
0
0
0
0
0
8
0
8
8
0
62
0
% P
% Gln:
0
0
8
16
0
8
85
0
0
0
0
54
0
0
8
% Q
% Arg:
0
0
70
0
0
0
0
0
0
0
0
8
62
0
62
% R
% Ser:
8
0
0
8
0
0
0
62
0
16
0
0
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
24
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
70
8
0
0
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _